We investigated the role of ferroptosis in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). By using an experimental model, we applied treatments with deferoxamine (DFO) and edaravone (EDA) to inhibit ferroptosis.
Our findings revealed that targeting ferroptosis may reduce inflammation, fibrosis, and mast cell activity, potentially easing pelvic pain associated with CP/CPPS. These results highlight a new pathway for treating this challenging condition, offering hope for improved management strategies.
Read More
7
Long-acting contraceptives offer health benefits
Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems.
We discovered that hormonal contraceptives, particularly long-acting systems like the levonorgestrel-releasing intrauterine device, provide significant non-contraceptive health benefits.
These benefits include the treatment of pelvic pain, especially in cases related to endometriosis, as well as management of heavy menstrual bleeding and iron deficiency.
Research highlights that these contraceptives are effective options for addressing various gynecological disorders beyond birth control.
Read More
5
Iron patch offers similar pain relief
Comparing the analgesic effect of heat patch containing iron chip and ibuprofen for primary dysmenorrhea: a randomized controlled trial.
We explored the effectiveness of a heat patch containing iron chips compared to ibuprofen for alleviating primary dysmenorrhea. In our randomized controlled trial involving 147 students, we examined pain severity and emotional impact using a standardized questionnaire.
Although we found that the heat patch provided comparable relief to ibuprofen, the differences in pain severity were not significant. This suggests that while the heat patch is a viable option, it may not be markedly more effective than ibuprofen for managing menstrual pain.
Read More
Most Useful Reviews
7.5
Eased menstrual pain
13 people found this helpful
Since I began this iron supplement, symptoms of anaemia and menstrual pain have improved. My menstruation feels lighter, and I'm able to work without discomfort. However, without proper iron intake, constipation can occur. This iron remedy seems to be a good alternative to others I've tried.
Read More
9
Less fatigue
11 people found this helpful
I switched to this 18 mg iron supplement after experiencing stomach pain with previous iron tablets. So far, I have had no stomach discomfort or constipation, and my energy levels have significantly improved. This product is now essential in my routine, making me feel lighter and more comfortable without anxiety over outings. Cycling again brings joy without tiring me significantly.
Read More
7.5
Increased energy
6 people found this helpful
I discovered that my minor ailments were due to iron deficiency, which has improved significantly since incorporating iron. Walking speed has increased, and I feel rejuvenated. I usually rely on medication for PMS, but now my menstrual flow is smoother, and I feel far more energetic and lighter.
We investigated the role of ferroptosis in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). By using an experimental model, we applied treatments with deferoxamine (DFO) and edaravone (EDA) to inhibit ferroptosis.
Our findings revealed that targeting ferroptosis may reduce inflammation, fibrosis, and mast cell activity, potentially easing pelvic pain associated with CP/CPPS. These results highlight a new pathway for treating this challenging condition, offering hope for improved management strategies.
Read More
7
Long-acting contraceptives offer health benefits
Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems.
We discovered that hormonal contraceptives, particularly long-acting systems like the levonorgestrel-releasing intrauterine device, provide significant non-contraceptive health benefits.
These benefits include the treatment of pelvic pain, especially in cases related to endometriosis, as well as management of heavy menstrual bleeding and iron deficiency.
Research highlights that these contraceptives are effective options for addressing various gynecological disorders beyond birth control.
Read More
7
Goserelin enhances hemoglobin but not pain
Goserelin acetate 10.8 mg plus iron versus iron monotherapy prior to surgery in premenopausal women with iron-deficiency anemia due to uterine leiomyomas: results from a Phase III, randomized, multicenter, double-blind, controlled trial.
We aimed to understand the impact of adding goserelin acetate to iron treatment in premenopausal women facing iron-deficiency anemia due to uterine fibroids.
In this Phase III trial, participants received either goserelin with iron or just iron over 12 weeks, followed by surgery. While women given goserelin showed higher hemoglobin levels, we didn’t find a significant improvement in symptoms like pelvic pain.
Overall, while goserelin helped with blood levels, it didn't make a noticeable difference in alleviating pelvic discomfort.
Read More
5
Lactoferrin benefits menstrual distress
Effects of a Bovine Lactoferrin Formulation from Cow's Milk on Menstrual Distress in Volunteers: A Randomized, Crossover Study.
Our study examined the effects of a lactoferrin formulation derived from cow's milk on menstrual symptoms in healthy women.
Conducted as a double-blind, randomized, placebo-controlled trial, we enrolled thirty-five Japanese volunteers who received either the iron-lactoferrin complex or a placebo.
While our findings showed improvements in psychological symptoms related to menstrual distress, such as reduced MDQ scores, other measures—like pain and quality of life—did not vary significantly.
Notably, no side effects were reported, suggesting this treatment could help with psychological discomfort linked to dysmenorrhea.
Read More
5
Iron patch offers similar pain relief
Comparing the analgesic effect of heat patch containing iron chip and ibuprofen for primary dysmenorrhea: a randomized controlled trial.
We explored the effectiveness of a heat patch containing iron chips compared to ibuprofen for alleviating primary dysmenorrhea. In our randomized controlled trial involving 147 students, we examined pain severity and emotional impact using a standardized questionnaire.
Although we found that the heat patch provided comparable relief to ibuprofen, the differences in pain severity were not significant. This suggests that while the heat patch is a viable option, it may not be markedly more effective than ibuprofen for managing menstrual pain.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 33 Reviews
7.3
All Reviews
Positive Reviews
Negative Reviews
7.5
Eased menstrual pain
13 people found this helpful
Since I began this iron supplement, symptoms of anaemia and menstrual pain have improved. My menstruation feels lighter, and I'm able to work without discomfort. However, without proper iron intake, constipation can occur. This iron remedy seems to be a good alternative to others I've tried.
Read More
9
Less fatigue
11 people found this helpful
I switched to this 18 mg iron supplement after experiencing stomach pain with previous iron tablets. So far, I have had no stomach discomfort or constipation, and my energy levels have significantly improved. This product is now essential in my routine, making me feel lighter and more comfortable without anxiety over outings. Cycling again brings joy without tiring me significantly.
Read More
7.5
Increased energy
6 people found this helpful
I discovered that my minor ailments were due to iron deficiency, which has improved significantly since incorporating iron. Walking speed has increased, and I feel rejuvenated. I usually rely on medication for PMS, but now my menstrual flow is smoother, and I feel far more energetic and lighter.
Read More
9
Effective iron boost
5 people found this helpful
This supplement effectively increases iron levels; my ferritin went from 21 to 57 within a month. I appreciate that it does not cause nausea, abdominal pain, or constipation. It is best taken between meals in the afternoon and should not be mixed with dairy products or other medications.
Read More
8
Lighter menstrual pain
4 people found this helpful
I've taken iron for the first time and was pleasantly surprised that it caused no gastrointestinal issues. Additionally, my menstrual pain has significantly reduced, which I believe is a direct result of this supplement.
Pelvic pain is a broad term that describes discomfort occurring in the lower abdomen or pelvic region. It can stem from various underlying conditions, involving reproductive organs, the urinary tract, or gastrointestinal issues. Common causes include menstrual cramps, endometriosis, pelvic inflammatory disease, ovarian cysts, and urinary tract infections. Additionally, pelvic pain can be acute, occurring suddenly and sharply, or chronic, lasting for six months or more, significantly impacting one’s quality of life.
Managing pelvic pain often begins with a thorough evaluation from a healthcare provider to determine the underlying causes. Treatment options can vary widely based on the diagnosis and may include medication for pain relief, physical therapy, lifestyle changes, or, in some cases, surgery. Lifestyle adjustments, such as heat therapy and relaxation techniques, can also provide relief. Given the diverse nature of pelvic pain, it’s essential for individuals experiencing persistent discomfort to consult a medical professional for an accurate diagnosis and personalized treatment plan.
Iron is a chemical element with the symbol Fe, derived from the Latin word "ferrum." It is a metal that is known for its strength and versatility, making it one of the most widely used materials in construction, manufacturing, and various industrial applications. Iron is the fourth most abundant element in the universe by mass and is primarily obtained through the mining of iron ores, such as hematite and magnetite. Once mined, it undergoes processes like smelting and refining to produce usable forms like cast iron, wrought iron, and steel.
In addition to its industrial uses, iron is also crucial for human health, as it plays a significant role in the production of hemoglobin, the protein in red blood cells responsible for transporting oxygen throughout the body. A deficiency in iron can lead to anemia, characterized by fatigue and weakened immunity. Overall, iron is a fundamental element that supports modern infrastructure and is vital for maintaining good health.
Based on user reviews, many individuals taking this iron supplement for pelvic pain and menstrual issues report seeing positive results within a few weeks to a month. For instance, one user mentioned that after one month, her haemoglobin levels improved significantly, alleviating both menstrual pain and PMS symptoms Read Review. Another review highlighted that after two months, dizziness and menstrual pain were greatly relieved Read Review.
Additionally, some users noted improvements in their symptoms shortly after starting the supplement, while others found that it took a little longer, depending on their individual health conditions Read Review. Consistent and correct usage, such as taking the supplement a few days prior to menstruation, has also been recommended for those specifically targeting pelvic pain Read Review. Overall, while results can vary, users generally report a trend of symptom improvement within a month.
Based on the exploration of chronic pelvic pain and its potential treatments, scientific research suggests that some supplements and therapies may provide relief. For instance, a study focusing on ferroptosis indicated that treatments aimed at inhibiting this process could potentially reduce inflammation and alleviate pain associated with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) [1]. Though this is a promising pathway, it remains an emerging area that requires further investigation.
Other supplements, such as cow's milk-derived lactoferrin, were tested for their effects on menstrual discomfort. While psychological symptoms improved, pain relief and overall quality of life enhancements were not significantly different from placebo treatments [2]. Additionally, hormonal contraceptives like the levonorgestrel-releasing IUD have shown efficacy in treating pelvic pain related to endometriosis [3]. Thus, while certain supplements and approaches hold potential, the efficacy for pelvic pain management varies and often requires further validation through comprehensive studies.
Based on user reviews, many individuals have reported significant improvements in their symptoms after starting this iron supplement. Users have notably found that menstrual pain, which was previously severe, has decreased considerably. For instance, one reviewer shared that their menstrual pain has lessened to the point where they can manage without pain relief medication Read Review. Another user noted that their iron deficiency symptoms, such as weakness during pregnancy and general malaise, improved markedly, allowing them to regain energy and experience a smoother menstrual flow Read Review.
Several users have also highlighted the absence of common gastrointestinal side effects typically associated with other iron supplements, such as nausea and constipation. One individual mentioned a shift from products that caused discomfort to this supplement, remarking on the absence of stomach pain alongside improved iron absorption Read Review. Others have noted gradual improvements in hemoglobin and ferritin levels, directly contributing to enhanced energy and wellbeing Read Review. While these anecdotal experiences are promising, it’s important to remember that individual results may vary, and what works for one may not work for another.
Based on user reviews, many individuals combining this iron supplement with other supplements for managing pelvic pain have reported positive experiences. Notably, one user mentioned the integration of primrose oil alongside the iron supplement, which notably reduced cramping, pain, and heavy menstrual flow. They found their symptoms significantly improved, particularly during the first day of their period, after implementing this combination Read Review. This suggests that certain supplemental pairings may enhance the overall effectiveness of managing pelvic pain and menstrual discomfort.
Additionally, some users highlighted the importance of timing in taking the iron supplement, further enhancing its contribution to pelvic pain relief. For instance, taking the iron shortly before or during menstruation was found to aid with abdominal pain Read Review. This indicates that while the iron supplement alone has been credited with notable improvements in managing symptoms, the combination with other supplements and strategic timing can potentially amplify its benefits for users dealing with pelvic pain.
Users reported various experiences with iron supplementation, focusing on its effects on pelvic pain and menstrual symptoms. Many individuals noted improvements in menstrual pain and discomfort after starting iron supplements. For instance, one user found that their menstrual pain was significantly reduced after taking iron consistently, indicating a direct correlation between the supplement and alleviation of symptoms (Read Review). Another review highlighted that taking iron before and during their period effectively lessened abdominal pain (Read Review).
Regarding dosage, users appear to have found 18 mg of iron both effective and gentle, as one reviewer switched to this amount after experiencing discomfort with other preparations (Read Review). Another user suggested beginning iron intake a few days prior to menstruation for optimal results, emphasizing its role in managing pain and cramping during their cycle (Read Review). Overall, while specific dosage recommendations weren't consistently mentioned, a pattern emerged favoring moderate doses and timing to enhance effectiveness for menstrual pain.
10
Cured period pain
1 people found this helpful
All women suffering from period pain and PMS should give this a go! It is often said that Japanese individuals lack iron. I tried several iron products, but my anaemia and haemoglobin levels did not improve. This chelated iron improved my anaemia remarkably in one month 😭 (haemoglobin rose from 9 to 15). It alleviated not only my menstrual pain but also the dreadful PMS, so I regard it as a miraculous supplement! I no longer feel irritable or lonely during PMS and am amazed every month at the sudden arrival of my period. I wish I had discovered it sooner; it’s far superior to the heme iron sold in pharmacies!
9
Dizziness relief
1 people found this helpful
After using this for two months, it has greatly relieved my dizziness and menstrual pain. I recommend it; it’s gentle on the stomach and does not cause constipation.
7.5
Less cramping noted
1 people found this helpful
I highly recommend this for PMS. Women should start taking it a few days before their period along with primrose oil, as it has significantly reduced my cramping, pain, and heavy flow, which previously lasted for 8 days. Now, I experience minimal cramping on the first day, and my period lasts for just 5 days.
8
Reduced menstrual pain
1 people found this helpful
This capsule is easy to take, lacking the unique smell of iron. After drinking iron tea for over half a year, my severe menstrual pain has lessened considerably, allowing me to manage without painkillers. I highly recommend this to women!
9
Anemia resolved
2 people found this helpful
I suffered from severe weakness during early pregnancy due to anaemia. After taking a double dose of iron, I quickly regained my energy. I continued during my pregnancy without experiencing another severe weakness; this supplement proved effective and gentle compared to others I've tried.
7.5
Reduced menstrual symptoms
9 people found this helpful
After switching from heme iron to this iron supplement, I have noticed a marked improvement in absorption without experiencing symptoms like abdominal pain or black stools. I feel it is particularly beneficial during my menstrual cycle. Iron is vital for women, and I have been trying various supplements, finding this one to be quite effective overall.
9
Effective iron boost
5 people found this helpful
This supplement effectively increases iron levels; my ferritin went from 21 to 57 within a month. I appreciate that it does not cause nausea, abdominal pain, or constipation. It is best taken between meals in the afternoon and should not be mixed with dairy products or other medications.
7
Helps with abdominal pain
1 people found this helpful
Taking this iron just before or during my period aids with abdominal pain. Although it has a slight iron taste, swallowing it quickly with plenty of water resolves the issue. The capsule is also smaller compared to other foreign supplements.
8
Lighter menstrual pain
4 people found this helpful
I've taken iron for the first time and was pleasantly surprised that it caused no gastrointestinal issues. Additionally, my menstrual pain has significantly reduced, which I believe is a direct result of this supplement.
9
Reduced abdominal pain
I purchased this product to alleviate lower abdominal pain during my period. I started taking it a few days before and during menstruation, and it genuinely helped. The pain was diminished by half, making me intend to use it every month. The tablets are of average size, easy to swallow, and have a neutral taste. I highly recommend this supplement!
9
Less fatigue
11 people found this helpful
I switched to this 18 mg iron supplement after experiencing stomach pain with previous iron tablets. So far, I have had no stomach discomfort or constipation, and my energy levels have significantly improved. This product is now essential in my routine, making me feel lighter and more comfortable without anxiety over outings. Cycling again brings joy without tiring me significantly.
7
Ferroptosis inhibition for pelvic pain
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis.
We investigated the role of ferroptosis in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). By using an experimental model, we applied treatments with deferoxamine (DFO) and edaravone (EDA) to inhibit ferroptosis.
Our findings revealed that targeting ferroptosis may reduce inflammation, fibrosis, and mast cell activity, potentially easing pelvic pain associated with CP/CPPS. These results highlight a new pathway for treating this challenging condition, offering hope for improved management strategies.
5
Lactoferrin benefits menstrual distress
Effects of a Bovine Lactoferrin Formulation from Cow's Milk on Menstrual Distress in Volunteers: A Randomized, Crossover Study.
Our study examined the effects of a lactoferrin formulation derived from cow's milk on menstrual symptoms in healthy women.
Conducted as a double-blind, randomized, placebo-controlled trial, we enrolled thirty-five Japanese volunteers who received either the iron-lactoferrin complex or a placebo.
While our findings showed improvements in psychological symptoms related to menstrual distress, such as reduced MDQ scores, other measures—like pain and quality of life—did not vary significantly.
Notably, no side effects were reported, suggesting this treatment could help with psychological discomfort linked to dysmenorrhea.
7
Long-acting contraceptives offer health benefits
Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems.
We discovered that hormonal contraceptives, particularly long-acting systems like the levonorgestrel-releasing intrauterine device, provide significant non-contraceptive health benefits.
These benefits include the treatment of pelvic pain, especially in cases related to endometriosis, as well as management of heavy menstrual bleeding and iron deficiency.
Research highlights that these contraceptives are effective options for addressing various gynecological disorders beyond birth control.
References
Lin D, Zhang M, Luo C, Wei P, Cui K, et al. Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis. J Immunol Res. 2022;2022:6833867. doi:10.1155/2022/6833867
Ueno HM, Yoshise RE, Sugino T, Kajimoto O, Kobayashi T. Effects of a Bovine Lactoferrin Formulation from Cow's Milk on Menstrual Distress in Volunteers: A Randomized, Crossover Study. Int J Mol Sci. 2016;17. doi:10.3390/ijms17060845
Fraser IS. Added health benefits of the levonorgestrel contraceptive intrauterine system and other hormonal contraceptive delivery systems. Contraception. 2013;87:273. doi:10.1016/j.contraception.2012.08.039
Navvabi Rigi S, Kermansaravi F, Navidian A, Safabakhsh L, Safarzadeh A, et al. Comparing the analgesic effect of heat patch containing iron chip and ibuprofen for primary dysmenorrhea: a randomized controlled trial. BMC Womens Health. 2012;12:25. doi:10.1186/1472-6874-12-25
Muneyyirci-Delale O, Richard-Davis G, Morris T, Armstrong J. Goserelin acetate 10.8 mg plus iron versus iron monotherapy prior to surgery in premenopausal women with iron-deficiency anemia due to uterine leiomyomas: results from a Phase III, randomized, multicenter, double-blind, controlled trial. Clin Ther. 2007;29:1682.